Histone methyltransferase G9a protects against acute liver injury through GSTP1
نویسندگان
چکیده
منابع مشابه
Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells.
Dimethylated histone H3 lysine 9 (H3K9me2) is a critical epigenetic mark for gene repression and silencing and plays an essential role in embryogenesis and carcinogenesis. Here, we investigated the effects of hypoxic stress on H3K9me2 at both global and gene-specific level. We found that hypoxia increased global H3K9me2 in several mammalian cell lines. This hypoxia-induced H3K9me2 was temporall...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2019
ISSN: 1350-9047,1476-5403
DOI: 10.1038/s41418-019-0412-8